Hemoperfusion is a specialized blood purification technique used to remove harmful substances — such as toxins, drugs, metabolic waste, or inflammatory molecules — directly from the blood. During hemoperfusion, the patient’s blood passes through a cartridge containing adsorbent materials (such as activated charcoal or resins) that selectively bind and remove unwanted substances. It is commonly used in poisoning, sepsis, liver failure, autoimmune diseases, and severe inflammatory conditions, often alongside dialysis or other extracorporeal therapies.
Hemoperfusion is a detoxification therapy where blood is circulated through an adsorbent cartridge that traps toxins or harmful molecules. Unlike dialysis, which removes small molecules through diffusion, hemoperfusion can eliminate larger, protein-bound toxins that are difficult to remove by conventional dialysis.
Your doctor may recommend hemoperfusion in the following situations:
It is also used as part of multi-organ support in critical care units.
Yes. When performed by experienced specialists, hemoperfusion is safe and effective.
Possible side effects are minimal and may include:
These are carefully monitored and managed by trained nephrology and critical care teams at BMH.
No — while both are blood purification therapies, they work differently:
| Aspect | Hemodialysis | Hemoperfusion |
| Mechanism | Diffusion through a membrane | Adsorption using a special cartridge |
| Removes | Small molecules (urea, creatinine, electrolytes) | Larger, protein-bound toxins, drugs, cytokines |
| Used in | Kidney failure | Poisoning, sepsis, liver failure, inflammation |
| Combination | Often used together | Enhances overall clearance |
In critical situations, both therapies may be combined for maximum benefit.
Hemoperfusion is performed by a specialized nephrology and critical care team — including nephrologists, intensivists, and trained dialysis nurses — under continuous monitoring of vital signs and blood parameters.
If you or a loved one is suffering from poisoning, severe infection, or toxin buildup, the Nephrology & Critical Care Team at Baby Memorial Hospital (BMH) offers advanced Hemoperfusion therapy — combining precision equipment, expert care, and 24x7 monitoring for safe and effective blood purification.
👉 Book an Appointment Online or visit BMH to consult our nephrology and critical care specialists.